Hugh F. Keefe didn’t earn his reputation as one of the state’s top criminal-defense lawyers by passing up high-profile cases.

But last Friday Keefe announced that he’s regrettably doing just that. He has withdrawn as the attorney for Martin Frankel, the Greenwich money manager accused of federal money laundering and wire fraud charges. That is “unless a miracle happens” and he is able to convince the government to unfreeze enough of Frankel’s assets to allow Frankel to mount an adequate defense, notes Keefe, of New Haven’s Lynch, Traub, Keefe and Errante.