The judicial philosophy and independence of a newly confirmed Justice Amy Coney Barrett will be tested almost immediately by a battery of U.S. Supreme Court challenges related to elections, Trump administration immigration policies, abortion, the Affordable Care Act and religion and LGBT discrimination.

The Republican-controlled Senate on Monday voted 52-48 to confirm President Donald Trump’s nomination of Barrett to fill the seat vacated by the Sept. 18 death of Barrett’s ideological opposite, Justice Ruth Bader Ginsburg.

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