Sofinnova Ventures Inc. is a marquee Sand Hill Road firm. Founded in 1974 and on its eighth fund, it manages approximately $1.4 billion in active client assets. In 2011 the company raised about $440 million for Fund VIII, its first focused exclusively on life science companies.

One of the oldest venture capital firms in Silicon Valley, Sofinnova originally sprang out of French investment firm Sofinnova SA and has a sister firm, Sofinnova Partners based in Paris. The two firms have been independent since the late 1990s.