In a case that is on track to be Philadelphia’s first trial over talc-related cancer, Johnson & Johnson has lost its bid to keep several experts from testifying about the alleged causal connection between talcum powder and ovarian cancer—a claim that has resulted in numerous so-called nuclear verdicts for injured women in other jurisdictions.

Philadelphia Judge Frederica Massiah-Jackson denied several motions J&J filed in the case, captioned Kleiner v. Rite Aid, that challenged methodologies used by six of the plaintiff’s experts to form their opinions that the company’s talcum powder causes cancer.

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