With potentially billions of dollars in licensing fees on the line, the Massachusetts Institute of Technology notched a key win Wednesday after the U.S. Patent and Trademark Office decided its gene-editing patents don’t conflict with a patent belonging to the University of California, Berkeley.

The USPTO ruling Wednesday effectively ends the debate between Berkeley and the Broad Institute at MIT over which was first to invent a technique known as CRISPR-Cas9 in multicellular organisms.

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