St. Louis-based Express Scripts, Inc., plans to buy rival Medco Health Solutions, Inc., in a $29.1 billion deal that would create the country’s largest pharmacy-benefit manager, the companies announced Thursday.

The deal is the second megadeal announced in a week. On Friday, BHP Billiton announced a $12.1 billion bid for oil and gas company Petrohawk Energy. Both transactions follow reports that the pace of M&A slowed during the second quarter of 2011 following a prodigious start to the year, suggesting that the market’s continued appetite for large deals has not yet been sated.

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