The Missouri Court of Appeals appeared disinclined to question a jury’s $4.7 billion talcum powder verdict but raised numerous jurisdictional questions about why the case against New Jersey-based Johnson & Johnson was in Missouri.

The case involved 22 women and their families alleging Johnson & Johnson’s baby powder, which contained asbestos, caused them to get ovarian cancer. On Friday, Johnson & Johnson attorney Thomas Weaver argued to reverse the verdict, focusing in large part on the fact that the judge should never have joined the claims of so many plaintiffs into a single trial, particularly since 17 of them were not from Missouri. He claimed that doing so prejudiced the jury, which awarded $25 million in compensatory damages to each plaintiff in 2018.