Three drug companies and a pharmacy insisted in a trial that began this week that they are not responsible for San Francisco’s opioid crisis. Instead, defense lawyers put much of the blame on a drug manufacturer that wasn’t there: Purdue Pharma, which is now in bankruptcy.

“Now, without the ability to try this case against Purdue, the people come into this court pointing at my clients and the other defendants in this case,” said Collie James, a partner at Morgan, Lewis & Bockius in Costa Mesa, California, in his opening statement on Tuesday for Teva. “But we are not Purdue.”