Federal prosecutors handling the government’s criminal case against Theranos founder Elizabeth Holmes have fired back at claims that they failed to allege any single fraudulent statement or misrepresentation made about the now-defunct blood-testing company.

In court papers filed Monday, prosecutors argued that they charged the wire fraud case against Holmes and her codefendant, former company president Ramesh Balwani, in a way that does not require them to prove any particular statement was false.