“The big one.” “A major victory.” “A game changer.” That’s how many lawyers in the defense bar described Monday’s landmark decision by the U.S. Supreme Court in Bristol-Myers Squibb v. Superior Court of California.

They’re not too far off. In mere hours, a judge in Missouri ended a pivotal trial over Johnson & Johnson’s baby powder because of the court’s decision, granting a mistrial in a courtroom in St. Louis, a venue favored by many plaintiffs.

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