The nation’s lethal-injection landscape has changed profoundly in the nearly seven years since the U.S. Supreme Court last confronted the issue. And that is reason enough for the justices to take a new look at this execution method, opponents and supporters of the death penalty say.

In late April, the justices will return to what has become a litigious, unsettled area of the law when they hear arguments in Glossip v. Gross, a challenge to Oklahoma’s lethal-injection protocol.

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