The U.S. Court of Appeals for the Federal Circuit will not revive a $2.5 billion jury award that Merck & Co. and subsidiary Idenix Pharmaceuticals won against Gilead Sciences in 2016.

The Federal Circuit agreed with U.S. District Judge Leonard Stark of the District of Delaware that Idenix’s 7,608,597 patent claimed far too many potential compounds to identify the specific 2′-methyl-up modified nucleoside that Gilead uses to treat hepatitis C.