Paul, Weiss, Rifkind, Wharton & Garrison won a eye-popping $393 million verdict for Edwards LifeSciences Corp. on Wednesday in its global patent fight with Medtronic Inc.

A federal jury in Wilmington found that Medtronic’s CoreValve system infringes a single Edwards patent relating to heart valve technology. Jurors found that the infringement was willful and awarded Edwards $388.8 million in lost profits and $4.8 million in reasonable royalties—pretty much exactly what Edwards asked for.