Skadden Arps Slate Meagher & Flom, Freshfields Bruckhaus Deringer and Davis Polk are advising on US drugs giant Pfizer’s bid to acquire UK rival AstraZeneca.

Pfizer’s offer of around £60bn follows a rejected bid from the US company in January. It is thought any potential takeover could turn hostile after AstraZeneca released a statement today saying it felt it “was not appropriate to engage in discussions with Pfizer”.