Starting with a single garbage truck in 1968, Huzienga built Waste Management Inc. into a Fortune 500 company. He purchased independent sanitation engineering companies, and by the time he took the company public in 1972, he had completed the acquisition of 133 small-time haulers. By 1983, Waste Management was the largest waste disposal company in the United States.The business model worked again with Blockbuster Video, which he started in 1985 and built into the leading movie rental chain nine years later. In 1996, he formed AutoNation and built it into a Fortune 500 company.

Huizenga was founding owner of baseball’s Florida Marlins and the NHL Florida Panthers — expansion teams that played their first games in 1993. He bought the NFL Miami Dolphins and their stadium for $168 million in 1994 from the children of founder Joe Robbie, but had sold all three teams by 2009.