Wyeth won the first case in a series of lawsuits over its hormone replacement drugs on Friday when a federal jury rejected a woman’s claim the drugs caused her breast cancer.

A jury ruled against Linda Reeves, 67, in her suit against the Madison, N.J.-based drug maker, the first of about 4,500 against Wyeth over hormone drugs Premarin and Prempro. During the four-week trial, Reeves acknowledged not reading information supplied with the drug and said she left it up to her doctor to decide whether it was appropriate to treat symptoms of menopause.