Manatt, Phelps & Phillips, a Los Angeles-based firm with about 300 lawyers, has expanded its health care and entertainment practices in a recent effort to bolster its financial performance and establish a presence on both coasts.

For more than 40 years, Manatt has been known as the California-based government firm with a client roster of high-profile actors and musicians such as Bob Dylan and the Rolling Stones. Now the firm is setting its sights on health care and corporate entertainment and media.