W. Mark Lanier, the Houston lawyer who won a $253.5 million verdict in August in the nation’s first Vioxx pharmaceutical suit, wants another shot at a big win. But he wants to do it in state — not federal — court, and on his own — not as part of a multidistrict litigation pool.

He resigned from a state liaison committee in the federal Vioxx MDL on Oct. 24 to concentrate on litigating individual Vioxx suits in state court.