Jurors in the Midwest’s first trial over the once-blockbuster painkiller Vioxx on Tuesday cleared the drug’s maker in the 2003 deadly heart attack of a 52-year-old woman.

A Madison County court jury in Edwardsville, Ill., deliberated over two days before siding with Merck & Co., which had argued that Patty Schwaller’s weight and other health issues might have posed risks that better explain her collapse and sudden death.