A Manhattan judge who says he is “willing to take a fresh look” at a request that has been greeted skeptically by many courts is scheduled to begin a hearing Tuesday on whether to allow the defendant in a high-profile murder case to submit expert testimony at trial about what makes people confess to crimes they did not commit.

Although nearly every other state judge to have considered the issue has refused to allow such evidence, Acting Supreme Court Justice Richard Carruthers (See Profile) ordered a pretrial Frye hearing in the case against Natavia Lowery (People v. Lowery, 5850-07), to consider whether it should be admitted.