A federal judge has refused to toss claims that a host of pharmaceutical companies caused the opioid crisis.

U.S. District Judge Dan Polster of the Northern District of Ohio issued the order, along with several others, Tuesday, in preparation for the first federal trial in the nation, scheduled for Oct. 21 in Cleveland. The orders are among numerous summary judgment rulings the judge has issued ahead of the trial, in which a jury must decide a case brought by two Ohio counties against more than a dozen opioid companies, including Johnson & Johnson, Purdue Pharma and McKesson Corp.

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