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Large-scale document review poses significant challenges to an organization. A number of factors are responsible, but they generally relate to what I call the document review conundrum – the constant challenge of dealing with large amounts of electronically stored information, with ever-increasing volumes and ever-decreasing budgets and time. Worse still, the risks of making a misstep are very significant. The good news is a solution is finally on the horizon, in the form of technology-assisted review. But as one problem is addressed, another is created in kind. Today, many are attempting to understand the difference between the different forms of this emerging technology category and to learn how they can get the most out of their investment. This article will address these issues head on.